Publications by authors named "L Carli"

Article Synopsis
  • The study evaluated the effectiveness and retention rate of secukinumab (SCK) in patients with axial spondyloarthritis (ax-SpA) using data from five Italian centers.
  • A total of 71 patients were analyzed, showing significant improvements in disease activity over 24 months, with BASDAI scores decreasing from 6.2 to 3.5 and ASDAS-CRP from 2.9 to 1.7.
  • Though 72% of patients remained on SCK after two years, those with fibromyalgia had a higher dropout rate, indicating that coexisting conditions may affect treatment adherence.
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Introduction: Despite Sleeve Gastrectomy (SG) being the most commonly performed bariatric surgery today, studies with over 5 years of follow-up show that patients undergoing SG have inferior weight loss compared to those undergoing Roux-en-Y gastric bypass (RYGB). The aim of this study was to examine differences in weight loss and the prevalence of weight regain between SG and RYGB up to 8 years after surgery.

Methods: Retrospective study including adult patients undergoing SG or RYGB between 2015 and 2018 at a tertiary center in Brazil.

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Objective: To assess the impact of different disease activity patterns-long quiescent (LQ), chronically active (CA) and relapsing-remitting (RR)-on health-related quality of life (HRQoL) in a cohort of patients with systemic lupus erythematosus (SLE).

Methods: A retrospective, monocentric analysis of prospectively collected data. Adult SLE outpatients were enrolled between 2017 and 2021.

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Objectives: To analyse the response to immunosuppressants (IS) in extrarenal flares of SLE to determine the most appropriate timing during follow-up for a change in therapeutic strategy.

Methods: Observational cohort study including a total of 81 patients with SLE with extrarenal flares requiring a change in IS over the period 2015-2022. Baseline clinical variables were described, and follow-up data at 1, 3, 6 and 12 months time-points were collected.

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