As of 2023, 69% of adults and 81% of teens in the U.S. use social media.
View Article and Find Full Text PDFComp Biochem Physiol A Mol Integr Physiol
January 2025
Immunoglobulin A (IgA) has been investigated as a stress biomarker with the potential to complement glucocorticoid measurements in welfare assessments. This study aimed to develop the methodology and validate an enzyme immunoassay (EIA) for quantifying IgA in feces (FIgA) of lions (Panthera leo), investigate excretion patterns of FIgA under baseline conditions in captive lions, and explore its relationship with fecal glucocorticoid metabolites (FGM). Feces were collected from 11 lions housed in stable social groups at four Spanish zoos over a period of two to six weeks.
View Article and Find Full Text PDFBackground: Lung cancer is the second leading cause of death in the United States. Lung cancer is often diagnosed in its late stage leading to a poor prognosis. Lung nodules are often described as indeterminate from CT scans resulting in lung biopsies that are invasive and may lead to complications.
View Article and Find Full Text PDFBackground: Deficiencies in risk assessment for patients with pulmonary nodules (PNs) contribute to unnecessary invasive testing and delays in diagnosis.
Research Question: What is the accuracy of a novel PN risk model that includes plasma proteins and clinical factors? How does the accuracy compare with that of an established risk model?
Study Design And Methods: Based on technology using magnetic nanosensors, assays were developed with seven plasma proteins. In a training cohort (n = 429), machine learning approaches were used to identify an optimal algorithm that subsequently was evaluated in a validation cohort (n = 489), and its performance was compared with the Mayo Clinic model.
Histological methods allow to characterize the developmental changes that occur in plant tissues during in vitro culturing of explants. Different procedures to assess these changes have been reported in the literature. Here we describe a simple histological procedure to evaluate the development of explants using the fixation with paraformaldehyde, embedding with methacrylate resin and staining with periodic acid Schiff's reagent and naphthol blue black.
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