Publications by authors named "L Calderoni"
Introduction: Molecular imaging of thyroid and parathyroid diseases has changed in recent years due to the introduction of new radiopharmaceuticals and new imaging techniques. Accordingly, we provided an clinicians-oriented overview of such techniques and their indications.
Areas Covered: A review of the literature was performed in the PubMed, Web of Science, and Scopus without time or language restrictions through the use of one or more fitting search criteria and terms as well as through screening of references in relevant selected papers.
Endocrinology application of molecular imaging: current role of PET/CT.
J Endocrinol Invest
October 2024
Background: In recent years, nuclear medicine imaging methods have proven to be of paramount importance in a wide variety of diseases, particularly in oncology, where they are crucial for assessing the extent of disease when conventional methods fall short. Moreover, nuclear imaging modalities are able to better characterize lesions using target agents related to specific pathways (e.g.
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- Whole body scans (WBS) using I-131 can help monitor patients with differentiated thyroid cancer but can yield false positives due to non-tumor conditions.
- A study analyzed 370 cases of false uptake, finding that most originated from non-tumoral diseases (55.1%) and benign tumors (29.5%), with a notable occurrence in various body regions.
- To ensure accurate diagnosis, it’s essential to interpret WBS results alongside patient history, serum thyroglobulin levels, and additional medical tests.
Monitoring therapy response in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with novel hormonal therapies, taxanes, and newly approved therapies is crucial for optimizing treatment. [Ga]Ga-prostate-specific membrane antigen (PSMA)-11 positron emission tomography/computed tomography (PSMA PET/CT) is a promising target for managing treatment in patients with prostate cancer. PSMA is overexpressed in patients with mCRPC; understanding how expression might change in patients undergoing treatment could determine its potential for guiding clinical decisions.
View Article and Find Full Text PDFBackground: Transarterial Radioembolisation (TARE) requires multidisciplinary experience and skill to be effective. The aim of this study was to identify determinants of survival in patients with hepatocellular carcinoma (HCC), focusing on learning curves, technical advancements, patient selection and subsequent therapies.
Methods: From 2005 to 2020, 253 patients were treated.