Publications by authors named "L Caballeria"
Background: Non-alcoholic fatty liver disease (NAFLD) is rapidly increasing alongside overweight and obesity, not only in adults but also in children and adolescents. It is unknown what impact the development of NAFLD in childhood may have in later life. The importance of early detection and treatment lies in its potential for progression to cirrhosis, liver cancer and liver-related death, as well as its associated extrahepatic comorbidities.
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- Liver cirrhosis is a significant global health issue that often goes undiagnosed until severe complications arise, highlighting the need for tools to identify at-risk individuals earlier.
- Researchers developed the LiverRisk score, utilizing demographic and lab data from a large international cohort to categorize individuals into different risk groups for future liver-related issues.
- The LiverRisk score demonstrated superior predictive accuracy for liver stiffness and related outcomes compared to existing serum biomarkers, effectively aiding in the identification of those at heightened risk for liver disease complications.
Objective: To investigate longitudinal changes in the liver stiffness measurement (LSM) in the general adult population without known liver disease and to describe its association with metabolic risk factors, with a special focus on subjects with non-alcoholic fatty liver disease (NAFLD) and dysglycemia.
Material And Methods: A longitudinal adult population-based cohort study was conducted in Catalonia. LSM was measured by transient elastography (TE) at baseline and follow-up (median: 4.
Dysglycemia in young women attenuates the protective effect against fatty liver disease.
Front Endocrinol (Lausanne)
December 2022
Introduction: Sexual dimorphism has been reported in non-alcoholic fatty liver disease (NAFLD), similar to the sex differences evident with cardiovascular disease. Type 2 diabetes mellitus (T2D) significantly increases the risk and severity of NAFLD, but there is scarce information on whether T2D or altered glucose metabolism can modify the prevalence of NAFLD in men and women of reproductive age.
Purpose: To investigate the relationship between age, sex and NAFLD in subjects with and without dysglycemia.