Publications by authors named "L C Turco"
Background & Aims: Venous thromboembolism (VTE) is a recognized complication of acutely ill patients, but its incidence and risk factors in those with cirrhosis are uncertain.
Methods: We retrospectively studied a consecutive cohort of cirrhosis patients non-electively admitted to our medical unit to determine the rates of symptomatic VTE during hospitalization. Firstly, we explored associations with baseline, clinical and laboratory characteristics using logistic regression.
Article Synopsis
- The study focuses on the effectiveness of two-dimensional shear wave elastography (2D-SWE) for detecting liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), which is crucial for early intervention.
- A meta-analysis of 20 studies involving over 2,200 participants revealed that 2D-SWE has strong diagnostic accuracy, with area under the curve values indicating excellent performance in identifying different stages of fibrosis and cirrhosis.
- Optimized cutoff values for diagnosing various fibrosis levels were established, highlighting the potential for uniform diagnostic standards in assessing liver health among MASLD patients.
Oncotherapy can shape intestinal microbiota, which, in turn, may influence therapy effectiveness. Furthermore, microbiome signatures during treatments can be leveraged for the development of personalised therapeutic protocols in cancer treatment based on the identification of microbiota profiles as prognostic tools. Here, for the first time, the trajectory of gut and salivary microbiota in a patient treated with Larotrectinib, a targeted therapy approved for diagnosed glioblastoma multiforme neurotrophic tyrosine receptor kinase () gene fusion-positive, has been accurately investigated.
View Article and Find Full Text PDFMicroplastics (MPs) are a threat of growing concern for living organisms as they exist in all ecosystems. The bidirectional communication between the gut, its microbiota, and the liver, has been conceptualized as gut-liver axis and may be influenced by environmental factors. MPs can cause intestinal and hepatic injuries, but there is still limited research exploring their impact on gut-liver axis.
View Article and Find Full Text PDFBackground & Aims: Patients with vascular liver diseases (VLD) are at higher risk of both severe courses of COVID-19 disease and thromboembolic events. The impact of SARS-CoV-2 vaccination in patients with VLD has not been described and represents the aim of our study.
Methods: International, multicenter, prospective observational study in patients with VLD analyzing the incidence of COVID-19 infection after vaccination, severity of side effects, occurrence of thromboembolic events and hepatic decompensation.