The NHS England Jewish BRCA Testing Programme: overview after first year of implementation (2023-2024).

Background: The NHS Jewish BRCA Testing Programme is offering germline and genetic testing to people with ≥1 Jewish grandparent. Who have an increased likelihood of having an Ashkenazi Jewish (AJ) founder germline pathogenic variant (gPV) compared with the general population.Testing is offered via a self-referral, home-based saliva sampling pathway, supported by a genetic counsellor telephone helpline.

Hidden in plain sight: Women and gendered dementia dynamics in the Australian Aged Care Royal Commission.

Dementia is known to unequally affect women, whether as women living with dementia, or women who provide unwaged or paid care, yet dementia and long-term care ('LTC') research and policy often ignore gender. Using Australia as a case study and building on critical dementia, critical disability, and feminist scholarship, this discourse analysis study explored representations in the Australian Royal Commission into Aged Care Quality and Safety ('ACRC') Final Report of experiences of women with dementia, and women care partners of people with dementia, using long-term care. This paper argues gender remained an overlooked topic in relation to dementia in the ACRC Final Report.

Cutaneous T cell lymphoma atlas reveals malignant T2 cells supported by a B cell-rich tumor microenvironment.

Cutaneous T cell lymphoma (CTCL) is a potentially fatal clonal malignancy of T cells primarily affecting the skin. The most common form of CTCL, mycosis fungoides, can be difficult to diagnose, resulting in treatment delay. We performed single-cell and spatial transcriptomics analysis of skin from patients with mycosis fungoides-type CTCL and an integrated comparative analysis with human skin cell atlas datasets from healthy and inflamed skin.

Co-design and evaluation of an audio podcast about sustainable development goals for undergraduate nursing and midwifery students.

Background: Sustainable Development Goals (SDGs) are universally recognised targets designed to combat poverty, inequality, and climate change. However, there exists limited awareness and understanding of these goals among nursing and midwifery students. To address this knowledge gap, a co-designed audio podcast was introduced as an educational tool to enhance students' comprehension of SDGs and their relevance to the healthcare profession.