Toward the Development of Standards for Yellow Flashing Lights Used in Work Zones.

Flashing yellow warning lights are important for worker and driver safety in work zones. Current standards for these lights do not address whether and how they should be coordinated to provide course-way information to drivers navigating through work zones. A field study in which the intensities and flash patterns of warning lights along a simulated work zone were varied during daytime and nighttime, was conducted to assess drivers' responses to different configurations, leading to several conclusions.

Glucose tolerance in mice exposed to light-dark stimulus patterns mirroring dayshift and rotating shift schedules.

Glucose tolerance was measured in (nocturnal) mice exposed to light-dark stimulus patterns simulating those that (diurnal) humans would experience while working dayshift (DSS) and 2 rotating night shift patterns (1 rotating night shift per week [RSS1] and 3 rotating night shifts per week [RSS3]). Oral glucose tolerance tests were administered at the same time and light phase during the third week of each experimental session. In contrast to the RSS1 and RSS3 conditions, glucose levels reduced more quickly for the DSS condition.

Circadian Disruption: comparing humans with mice.

Disruption of the 24-h light-dark cycle has been implicated as an endocrine disruptor and linked to increased morbidity and mortality in animal studies. Previously reported measurements of circadian disruption in day-shift and rotating-shift nurses were compared with new mouse data where the light-dark patterns simulated shiftwork. Phasor magnitudes, a measure of circadian entrainment, were shown to be similar for humans and for mice when exposed to similar patterns of light and dark.