Publications by authors named "L C Quilty"
Interpersonal psychotherapy (IPT) and antidepressant medications are both first-line interventions for adult depression, but their relative efficacy in the long term and on outcome measures other than depressive symptomatology is unknown. Individual participant data (IPD) meta-analyses can provide more precise effect estimates than conventional meta-analyses. This IPD meta-analysis compared the efficacy of IPT and antidepressants on various outcomes at post-treatment and follow-up (PROSPERO: CRD42020219891).
View Article and Find Full Text PDFIntroduction: People with lived and living experience (PWLLE) and family members (F) can engage in mental health and substance use health research beyond participant roles, as advisors, co-researchers, equal partners and research leads. However, implementing meaningful and effective engagement is complex.
Methods: This article profiles five research initiatives involving different lived experience engagement structures, situated in a single tertiary care teaching and research hospital.
Article Synopsis
- Current antidepressants show limited effectiveness, prompting research to identify biological targets for new treatments and understand their mechanisms.
- The study utilized EEG data from two Canadian trials to examine how changes in brain wave patterns (neural oscillations) correlate with symptom improvement in patients undergoing pharmacological and CBT treatments.
- Findings indicate that early increases in theta waves and late changes in delta and alpha waves are linked to better treatment outcomes, with common patterns observed in both treatment methods, enhancing our understanding of how depression treatments work.
Article Synopsis
- Major depressive disorder (MDD) affects about 250 million people globally, highlighting the need for effective treatment strategies that consider factors like chronotype (individual preference for morning or evening activities) and the timing of therapy sessions.
- A study involving 227 outpatients diagnosed with MDD examined how their chronotype and the time of day they received cognitive behavioral therapy influenced their post-treatment depression severity.
- Findings showed increases in morningness for those in the afternoon and evening therapy groups, with a significant connection between changes in morningness and depression severity for the afternoon group, although the lack of a control group limits the study's conclusions.
Adult playfulness describes the personality of the quick initiation and strong intensity of enjoyable experiences coupled with the frequency of engaging in playful behaviors. In addition to examining the reliability and validity of the Short Measure for Adult Playfulness (SMAP), we compared the psychometric properties of the SMAP across (a) 4- and 7-point answer formats; (b) German and English language versions; and (c) gender. The SMAP and criterion validity measures were distributed across three independent samples from Canada ( = 1,177) and a German sample ( = 660).
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