Factors that Influence Applicant Choice of In-Person versus Virtual Interview Format.

Background: Governing bodies of graduate medical education recommend conducting interviews virtually. Although most programs remain compliant with this guidance, it is unclear if this is broadly supported by interviewees. Virtual interview (VI), in-person interview (IPI), and virtual interview with an optional in-person visit (VI+) formats have unique strengths and weaknesses.

digitalMALDI: A Single-Particle-Based Mass Spectrometric Detection System for Biomolecules.

The development of a real-time system for characterizing individual biomolecule-containing aerosol particles presents a transformative opportunity to monitor respiratory conditions, including infections and lung diseases. Existing molecular assay technologies, although effective, rely on costly reagents, are relatively slow, and face challenges in multiplexing, limiting their use for real-time applications. To overcome these challenges, we developed digitalMALDI, a laser-based mass spectrometry system designed for single-particle characterization.

Adaptation of clinical bacteriology techniques for remote polar research.

Unlabelled: Remote polar regions offer unique opportunities and significant challenges for antimicrobial resistance research in a near-pristine environment. While core microbiology techniques continue to have an important role in supporting environmental research, the severe cold climate presents considerable challenges to laboratory research. We explore adaptations required for core bacteriology investigations in polar regions on an unsupported remote expedition c.

Point-of-care tests, diagnostic uncertainty and antimicrobial stewardship in the ICU: procalcitonin or PCR to aid antibiotic-stop decisions - an observational cohort study.

Objectives: Intensive care unit (ICU) clinicians stop antibiotics more often, with a negative infection: point-of-care test (PCR-POCT). Simulated cases of diagnostic uncertainty regarding infection resolution led clinicians to choose options such as procalcitonin (PCT) and/or PCR-POCTs +/- de-escalation to aid stop decisions. We hypothesised that a direct infection indicator, PCR-POCT, would influence stop judgements more than indirect PCT.

Individual and Joint Associations Between Animal and Plant Protein Intakes with Impaired Fasting Glucose and Type 2 Diabetes in the Framingham Offspring Study.

Objectives: Given the considerable discrepancy in the literature regarding dietary protein and glucose homeostasis, we examined the prospective association between protein intake (total, animal, plant) and risk of type 2 diabetes mellitus or impaired fasting glucose (IFG). We also examined whether these associations differed by sex, body weight, or other risk factors.

Methods: We included 1423 subjects, aged ≥ 30 years, in the Framingham Offspring Study cohort.