Publications by authors named "L C Martine"

Article Synopsis
  • Milk thistle seed oil, derived from Silybum marianum and the lesser-known Silybum eburneum, is being investigated for its health benefits, particularly in antioxidant properties.
  • This study compares the lipid and phenolic profiles of the seed oils from both species and highlights their high content of unsaturated fatty acids and beneficial phytosterols.
  • The oils demonstrated strong antioxidant activities, protecting THP-1 cells from oxidative stress linked to age-related diseases, suggesting they may be valuable for nutrition and disease prevention.
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Cholesterol is a major lipid of the animal realm with many biological roles. It is an important component of cellular membranes and a precursor of steroid hormones and bile acids. It is particularly abundant in nervous tissues, and dysregulation of cholesterol metabolism has been associated with neurodegenerative diseases such as Alzheimer's and Huntington's diseases.

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Omega-3 (n-3) polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA), are required for the structure and function of the retina. Several observational studies indicate that consumption of a diet with relatively high levels of n-3 PUFAs, such as those provided by fish oils, has a protective effect against the development of age-related macular degeneration. Given the accumulating evidence showing the role of gut microbiota in regulating retinal physiology and host lipid metabolism, we evaluated the potential of long-term dietary supplementation with the Gram-positive bacterium Lactobacillus helveticus strain VEL12193 to modulate the retinal n-3 PUFA content.

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Article Synopsis
  • * The study aims to investigate the transport dysfunction of long-chain polyunsaturated fatty acids (LC-PUFA) in the fetoplacental unit and its link to ROP by evaluating the relationship between placental fatty acid receptor expression and ROP occurrence.
  • * If the study finds a correlation, it could identify new mechanisms behind ROP, thereby aiding in public health strategies to prevent this condition in vulnerable infants.
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Plasmalogens (Pls) are glycerophospholipids that play critical roles in the brain. Evidence supports the role of diet and that of the gut microbiota in regulating brain lipids. We investigated the impact of dietary intake of inulin-a soluble fiber used as prebiotic-on the Pl content of the cortex in mice.

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