Eribulin exerts multitarget antineoplastic activity in glioma cells.

Background: Gliomas, particularly glioblastomas, are highly aggressive cancers with rapid proliferation and poor prognosis. Current treatments have limited efficacy, highlighting the need for new therapeutic strategies. Eribulin mesylate, a synthetic macrocyclic ketone, has shown potential as an anticancer agent in several malignancies.

Burkitt's Lymphoma of the Uterine Cervix in a Woman with Advanced HIV Disease: A Case Report on Challenges with Its Management in a Low Resource Setting.

Background: Burkitt's lymphoma (BL) affecting the female genital tract is rare.

Objective: The aim of this paper is to report BL of the cervix in an HIV-positive patient to discuss the fatality of the condition and ways to mitigate it through advocacy for improved health care delivery in resource limited settings.

Methods: The patient was a 29-year-old woman, Para 1, with abnormal vaginal bleeding for a month and living with HIV and had a CD4 of 26 cells/μL.

Clinical Outcomes of Fully Arthroscopic Versus Arthroscopically Assisted Latissimus Dorsi Transfer for Irreparable Subscapularis Tear.

Background: Untreated chronic subscapularis (SSC) tears pose a challenging problem to treat owing to the resultant tendon retraction, atrophy, fatty infiltration, and changes in humeral head position, which complicate surgical options. Anterior latissimus dorsi (LD) transfer has shown effective results in treating these tears without glenohumeral arthritis.

Purpose/hypothesis: This study introduces and evaluates fully arthroscopic and arthroscopically assisted anterior LD transfer techniques for reconstructing irreparable SSC tears.

Influence of build angle, printing layer thickness and aging on the flexural strength, precision, roughness and porosity analysis of a printed resin for provisional restorations.

Evaluate the impact of printing parameters on flexural strength (σ), flexural modulus (E), precision, and surface topography characteristics of a resin used to produce provisional restorations. 450 bars for provisional restorations were printed using the SLA printing (25 × 2x2mm ISO-4049), and randomly divided into 30 groups (n = 15) according to the following factors: "printing layer thickness" (25 μm;50 μm;100 μm), "Build angle" (0°,30°,45°,60°,90°) and "thermocycling-TC" (with or without). Following printing, the samples underwent cleaning with isopropyl alcohol.

Phylogeography of SARS-CoV-2 Omicron sublineages detected in asymptomatic blood donors during third epidemiological wave in Mato Grosso, Midwestern Brazil.

Emerging infectious disease agents represent pathogens that may evade current screening protocols while posing significant transfusion transmission risks regionally. This study investigated the prevalence of SARS-CoV-2 and other respiratory viruses among 633 blood donors at the MT-Hemocentro from November 2021 to February 2023. Nucleic acid obtained from nasopharyngeal swabs were tested by RT-qPCR for SARS-CoV-2, RSV, FLU-A, and FLU-B.