Publications by authors named "L C Lilly"
Objective: Recent U.S. registry publications showed no improvement in long-term survival post-liver transplant in the last three decades.
View Article and Find Full Text PDFArticle Synopsis
- Many liver transplantation programs no longer require a set period of abstinence for candidates, but effective monitoring for ongoing alcohol use is necessary.
- Urinary ethyl glucuronide (EtG) testing is highlighted as an objective measure to detect alcohol consumption in patients with alcohol-associated liver disease (ALD) during the pretransplant phase.
- In a study of 497 ALD patients, only 8% tested positive for EtG, with severe alcohol use disorder, lower daily consumption, and prolonged substance use being significant factors linked to positive results; psychiatric issues were not strongly related.
Aim: To investigate the efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 (SGLT2) inhibitors in liver transplant (LT) recipients with diabetes.
Methods: A single-centre, retrospective analysis of prospectively collected data from an LT recipient database (1990-2023) was conducted. We included adults with pre-existing diabetes and post-transplant diabetes, newly started on GLP-1RAs and/or SGLT2 inhibitors after LT.
Living donor liver transplantation (LDLT) offers the opportunity to decrease waitlist time and mortality for patients with autoimmune liver disease (AILD), autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. We compared the survival of patients with a potential living donor (pLDLT) on the waitlist versus no potential living donor (pDDLT) on an intention-to-treat basis. Our retrospective cohort study investigated adults with AILD listed for a liver transplant in our program between 2000 and 2021.
View Article and Find Full Text PDFBackground: Advanced donor age paired with donation after cardiac death (DCD) increases the risk of transplantation, precluding widespread use of grafts from such donors worldwide. Our aim was to analyze outcomes of liver transplantation using grafts from older DCD donors and donation after brain death (DBD) donors.
Methods: Patients who underwent liver transplantation using grafts from deceased donors between January 2016 and December 2021 were included in the study.