Publications by authors named "L C Kingry"
Bacterial zoonoses are established causes of severe febrile illness in East Africa. Within a fever etiology study, we applied a high-throughput 16S rRNA metagenomic assay validated for detecting bacterial zoonotic pathogens. We enrolled febrile patients admitted to 2 referral hospitals in Moshi, Tanzania, during September 2007-April 2009.
View Article and Find Full Text PDFAnaplasma bovis-Like Infections in Humans, United States, 2015-2017.
Emerg Infect Dis
September 2023
Article Synopsis
- Researchers found the DNA of a bacteria similar to Anaplasma bovis in blood samples from 4 patients in the US suspected of having tickborne illnesses.
- The new agent shows a molecular link to A. bovis-like bacteria found in Dermacentor variabilis ticks from various states.
- This suggests a possible connection between these patients’ illnesses and ticks carrying this specific bacterium.
Background: Tick-borne relapsing fever (TBRF) is a globally prevalent, yet under-studied vector-borne disease transmitted by soft and hard bodied ticks. While soft TBRF (sTBRF) spirochetes have been described for over a century, our understanding of the molecular mechanisms facilitating vector and host adaptation is poorly understood. This is due to the complexity of their small (~ 1.
View Article and Find Full Text PDFArticle Synopsis
- Reported cases of tick-borne diseases have increased in the U.S., primarily caused by bacteria, leading to challenges in clinical diagnosis due to similar symptoms.
- Traditional lab methods often fail during the acute phase of illness, but a new 16S rRNA gene PCR with next-generation sequencing (NGS) has been developed to improve early detection of these infections.
- This new method showed comparable performance to existing CDC methods, accurately detecting a wide range of tick-borne bacteria in blood samples.