Publications by authors named "L C Huard"

Background: Tracheal intubation (TI)-associated cardiac arrest (TI-CA) occurs in 1.7% of pediatric ICU TIs. Our objective was to evaluate resuscitation characteristics and outcomes between cardiac arrest patients with and without TI-CA.

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  • The study focused on pediatric in-hospital CPR events, particularly those involving bradycardia with poor perfusion, to evaluate the effects of early epinephrine on survival outcomes in children.
  • Researchers analyzed data from the ICU-RESUS trial, which involved CPR events that lasted 2 minutes or longer, examining the timing of epinephrine administration and the development of pulselessness.
  • Findings indicated that early epinephrine did not significantly improve the chances of survival or favorable neurological outcomes, while a high percentage of patients experienced pulselessness within the first few minutes of CPR.
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Objectives: Data to support epinephrine dosing intervals during cardiopulmonary resuscitation (CPR) are conflicting. The objective of this study was to evaluate the association between epinephrine dosing intervals and outcomes. We hypothesized that dosing intervals less than 3 minutes would be associated with improved neurologic survival compared with greater than or equal to 3 minutes.

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Adult and pediatric studies provide conflicting data regarding whether post-cardiac arrest hypoxemia, hyperoxemia, hypercapnia, and/or hypocapnia are associated with worse outcomes. We sought to determine whether postarrest hypoxemia or postarrest hyperoxemia is associated with lower rates of survival to hospital discharge, compared with postarrest normoxemia, and whether postarrest hypocapnia or hypercapnia is associated with lower rates of survival, compared with postarrest normocapnia. An embedded prospective observational study during a multicenter interventional cardiopulmonary resuscitation trial was conducted from 2016 to 2021.

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  • The study investigated the effectiveness of extracorporeal membrane oxygenation (ECPR) for pediatric patients who did not respond to traditional cardiopulmonary resuscitation (CPR) methods, focusing on early hemodynamics and end-tidal carbon dioxide (ET CO2) levels as potential indicators for survival and neurologic outcomes.
  • Data was collected from 97 ECPR patients across 18 ICUs from 2016-2021, revealing that most patients were under one year old and had congenital heart disease; only 41% of patients survived with favorable neurologic outcomes.
  • The study found no significant differences in blood pressure measures or chest compression rates between those who survived
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