: Cognition plays a major role in prosthetic rehabilitation success. The ability to identify patients who may have difficulty understanding and adapting to the rehabilitation process is beneficial for clinicians and patients to allow for targeted and appropriate therapy. The research aim was to codesign a process that facilitates routine cognitive screening into the amputee inpatient journey.
View Article and Find Full Text PDFObjective: Integrating Patient-Reported Outcome Measures (PROMs) into clinical practice is increasing, with research showing benefits in patient outcomes. However, evidence regarding patient's acceptance of PROMs is limited. Sydney Cancer Survivorship Centre (SCSC) clinic is a multidisciplinary clinic where clinicians use PROMs to guide patient consultation.
View Article and Find Full Text PDFThe world could witness another pandemic on the scale of COVID-19 in the future, prompting calls for research into how social and behavioral science can better contribute to pandemic response, especially regarding public engagement and communication. Here, we conduct a cost-effectiveness analysis of a familiar tool from social and behavioral science that could potentially increase the impact of public communication: survey experiments. Specifically, we analyze whether a public health campaign that pays for a survey experiment to pretest and choose between different messages for its public outreach has greater impact in expectation than an otherwise-identical campaign that does not.
View Article and Find Full Text PDFResponding to global standards and legislative updates in Canada, including Bill S-5 (2023), toxicity testing is shifting towards more ethical, methods. Traditional two-dimensional (2D) monolayer cell cultures, limited in replicating the complex environment, have prompted the development of more relevant three-dimensional (3D) spheroidal hepatocyte cultures. This study introduces the first 3D spheroid model for McA-RH7777 cells, assessing xenobiotic receptor activation, cellular signaling, and toxicity against dexamethasone and naphthenic acid (NA)-fraction components; NAFCs.
View Article and Find Full Text PDFThe oil sands area of northern Alberta has river sediments that contain natural bitumen. Eggs and fish in these rivers may be exposed to bitumen-related chemicals early in life. This paper assesses a short embryo-larval fish exposure to oil sands sediment and follows the fish behaviour as they mature in clean water and examines their breeding success as adults (5 months afterwards).
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