J Am Pharm Assoc (2003)
November 2024
Background: The 2024 Standards of Care in Diabetes recommend initiation of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) prior to starting basal insulin and to reconsider initiating a GLP-1 RA before starting bolus insulin if not already initiated. GLP-1 RA addition leads to improved glycemic benefits as well as risk reduction of cardiovascular and renal outcomes in patients with a history of these events. While there is evidence demonstrating the trends of insulin reduction or discontinuation following GLP-1 RA initiation, data regarding longer-term durability of GLP-1 RA use to sustain patients off bolus insulin are lacking.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
January 2025
Objective: To characterize the concerns of head and neck cancer (HNC) patients and discern changes in quality-of-life (QoL) during long-term follow-up.
Study Design: Retrospective review.
Setting: Survivorship clinic at a tertiary academic center.
Objectives: We characterize functional outcomes in head and neck cancer of unknown primary (CUP) based on primary site identification.
Methods: In this retrospective study, CUP cases were categorized as known primaries (KP) if a tumor was localized after diagnostic workup or persisting unknown primaries (UP). Age, sex, HPV status, diagnostic methods, and treatments regimens were collected.
Importance: The global prevalence of myopia is predicted to approach 50% by 2050, increasing the risk of visual impairment later in life. No pharmacologic therapy is approved for treating childhood myopia progression.
Objective: To assess the safety and efficacy of NVK002 (Vyluma), a novel, preservative-free, 0.