Publications by authors named "L Busakwe"

Article Synopsis
  • High HIV retention rates in South Africa's public primary care facilities are challenged by various barriers, but some facilities manage to excel despite these issues by leveraging a Positive Deviance approach to identify their strengths.
  • An extensive study, including interviews and focus groups, revealed key traits of successful facilities such as compassionate care, high staff morale, efficient workflows, and welcoming environments.
  • Based on these findings, a new intervention called the Connect intervention was developed, focusing on staff support, improving workflow, and enhancing the physical setting of care to boost patient retention in lower-performing facilities.
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Multidrug-resistant TB (MDR-TB) treatment for children frequently includes unpalatable drugs with low overall acceptability. This can negatively impact children and their caregivers´ treatment experiences and is an important contributor to poor adherence, and potentially, poor treatment outcomes. Children and their caregivers´ preferences for MDR-TB treatment are not well documented.

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Tuberculosis is the number one infectious cause of death globally. Young children, generally those younger than 5 years, are at the highest risk of progressing from tuberculosis infection to tuberculosis disease and of developing the most severe forms of tuberculosis. Most current tuberculosis drug formulations have poor acceptability among children and require consistent adherence for prolonged periods of time.

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We conducted a qualitative exploration into the palatability and acceptability of a novel fixed-dose combination (FDC) anti-tuberculosis drug. This study was nested in the SHINE (Shorter treatment for minimal TB in children) trial, which compares the safety and efficacy of treating non-severe drug-susceptible tuberculosis (TB) with a 6 vs. 4 months anti-tuberculosis regimen in children aged 0-16 years.

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