Publications by authors named "L Burnett"
Background: Scandium-47 is the therapeutic counterpart to the diagnostic radionuclides, Sc and Sc. Together, these form elementally matched theranostic nuclide pairs, but their incorporation into radiopharmaceuticals requires developing production techniques leading to radioscandium isotopes with high chemical and radionuclidic purity. Previous Sc production methods involved expensive, enriched titanium targets that require additional procedures for target recovery.
View Article and Find Full Text PDFPurpose: The Australian Genomics Cardiovascular Disorders Flagship was a national multidisciplinary collaboration. It aimed to investigate the feasibility of genome sequencing (GS) and functional genomics to resolve variants of uncertain significance (VUS) in the clinical management of patients and families with cardiomyopathies, primary arrhythmias, and congenital heart disease (CHD).
Methods: Between April 2019 and December 2021, 600 probands meeting cardiovascular disorder criteria from 17 cardiology and genetics clinics across Australia were enrolled in the Flagship and underwent GS.
Article Synopsis
- Dogs are crucial in forensic science due to their exceptional ability to detect scents, particularly for drugs and explosives.
- The study involved two groups of dogs – sport detection dogs and law enforcement explosive detection dogs – to assess how their sniffing dynamics change with training on specific odorants.
- Results showed that dogs increased their sniffing frequency as they gained experience with target odors, with law enforcement dogs taking in larger volumes of air compared to sport detection dogs.
Background: Genomic sequencing technology allows for identification of reproductive couples with an increased chance, as compared with that in the general population, of having a child with an autosomal recessive or X-linked genetic condition.
Methods: We investigated the feasibility, acceptability, and outcomes of a nationwide, couple-based genetic carrier screening program in Australia as part of the Mackenzie's Mission project. Health care providers offered screening to persons before pregnancy or early in pregnancy.
Article Synopsis
- Radiation dermatitis is a common side effect for head and neck cancer patients undergoing radiotherapy, and this study explores the use of KeraStat Cream (KC), a keratin-based treatment, as a potential remedy.* -
- In a pilot study, patients receiving definitive or postoperative radiotherapy were randomly assigned to either KC or standard care, focusing on adherence, reported skin reactions, and quality of life related to skin.* -
- The study included 24 patients with similar adherence rates between the two treatments but found no significant differences in radiation dermatitis, suggesting the need for a larger study to confirm KC's effectiveness.*