Publications by authors named "L Burghaus"

An Indian migrant presented with increasing neurological symptoms after an acute influenza B infection. We diagnosed progressive neurotuberculosis—a rare and difficult case of tuberculosis and influenza co-infection. It highlights the importance of broad-based diagnostics in people from low- and middle-income countries, taking into account unusual manifestations of tuberculosis.

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Background And Purpose: Status epilepticus (SE) is a neurological emergency due to prolonged seizure activity or multiple seizures without full recovery in between them. Prehospital SE management is crucial since its duration is correlated with higher morbidity and mortality rates. We examined the impact of different therapeutic strategies in the prehospital setting with a focus on levetiracetam.

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Article Synopsis
  • The study aimed to investigate the treatment practices and effectiveness of benzodiazepines (BZDs) for patients experiencing status epilepticus (SE) in Cologne over two years.
  • Out of 328 SE patients, only 72% were treated with BZDs initially, and just 21.6% received adequate doses as per guidelines; older patients and those with non-generalised seizures were less likely to be treated.
  • The findings suggest that proper BZD dosing can significantly improve outcomes in generalised convulsive SE, while aggressive treatment in non-generalised forms may worsen results, highlighting the need for more research on treatment for these cases.
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Background: Excessive daytime sleepiness (EDS) is a core narcolepsy symptom, for which solriamfetol (Sunosi®) was recently approved in the European Union. SURWEY characterises real-world strategies used by physicians when initiating solriamfetol, and patient outcomes after follow-up.

Methods: SURWEY is an ongoing retrospective chart review conducted by physicians in Germany/France/Italy.

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Background And Purpose: Sex differences in the clinical findings and the polysomnographic presentation of patients with obstructive sleep apnea (OSA) are compelling current research issues. For example, patients suffering from obstructive sleep apnea are predominantly male. While women are older than men and tend to have a higher body mass index, men typically present with a more severe form of obstructive sleep apnea.

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