J Community Hosp Intern Med Perspect
November 2024
Paraneoplastic limbic encephalitis (PLE) is a poorly understood condition, thought to be caused by the cross-reacting of tumor antibodies with neurons in the brain, resulting in neuropsychiatric sequelae, such as personality and behavioral changes, psychosis, memory loss, and seizures. Anti-contactin-associated protein-like 2 (CASPR2) antibodies can cause PLE in patients with particular tumors, which in most cases can be identified as thymoma, lung cancer, or endometrial cancer. Some case reports show rare instances with other tumors, such as throat or sigmoid carcinoma.
View Article and Find Full Text PDFIn the paper we present a solution for controlling the chain of bidirectional optical amplifiers, intended for long-haul fiber links used to distribute signals produced by optical atomic clocks. The solution is based on a dedicated two-channel noise detector, which allows independent measurement of the noise contributions related to interferometric signal fading and additive wideband noise. New signal quality metrics, based on two-dimensional noise detector, allows to distribute properly the needed gain among the chained amplifiers.
View Article and Find Full Text PDFIEEE Trans Ultrason Ferroelectr Freq Control
February 2023
The paper addresses the problem of a systematic frequency error occurring in semiconductor-laser frequency-synchronization circuits based on counting the beat note between the two lasers in a reference time interval using a high-frequency prescaler. Such synchronization circuits are suitable for operation in ultra-precise fiber-optic time-transfer links, used e.g.
View Article and Find Full Text PDFRetrospective chart review (RCR) studies rely on the collection and analysis of documented clinical data, a process that can be prone to errors. The aim of this study was to develop a defined set of criteria to evaluate RCR datasets for potential data errors. The Data Error Criteria (DEC) were developed by identifying data coding and data entry errors via literature review and then classifying them based on error types.
View Article and Find Full Text PDFThe data in this article are associated with the research paper "GigaAssay - an adaptable high-throughput saturation mutagenesis assay" [1]. The raw data are sequence reads of HIV-1 cDNA amplified from cellular genomic DNA in a new single-pot saturation mutagenesis assay designated the "GigaAssay". A bioinformatic pipeline and parameters used to analyze the data.
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