Publications by authors named "L Bubnova"
HLA Genotypes in Patients with Infection Caused by Different Strains of SARS-CoV-2.
Int J Environ Res Public Health
October 2022
The aggressive infectious nature of SARS-CoV-2, its rapid spread, and the emergence of mutations necessitate investigation of factors contributing to differences in SARS-CoV-2 susceptibility and severity. The role of genetic variations in the human HLA continues to be studied in various populations in terms of both its effect on morbidity and clinical manifestation of illness. The study included 484 COVID-19 convalescents (northwest Russia residents of St.
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- There has been a significant rise in tick bites among people in northern European Russia, coinciding with notable climate changes, like increased air temperatures.
- The study uses official statistics on human tick bites to analyze the impact of climate change on tick populations, which is challenging to study in the field due to the large area involved.
- An S-shaped relationship between the number of tick-bite victims and average annual air temperature, described by "Verhulst's law" (logistic function), indicates that tick population dynamics are influenced by temperature rather than time.
Background: Nowadays, there is no doubt that the development of infectious process is determined not only by individual features of a human, but also by features of infection agent. It is commonly known that ability to form an adequate immune response is based on immunogenetic peculiarities of macroorganism.
Methods: The immunogenetic study was performed in 228 children from 1 to 15 years old with different manifestations of tuberculosis (TB).
Aim: To study the specific features of de novo acute myeloid leukemia (AML) with FLT3-ITD mutation.
Subjects And Methods: The results of examination were analyzed in 101 patients. Bone marrow morphological specimens were stained with Pappenheim stain.
In the last fifteen years, published reports have described KIR gene-content frequency distributions in more than 120 populations worldwide. However, there have been limited studies examining these data in aggregate to detect overall patterns of variation at regional and global levels. Here, we present a summary of the collection of KIR gene-content data for 105 worldwide populations collected as part of the 15th and 16th International Histocompatibility and Immunogenetics Workshops, and preliminary results for data analysis.
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