Publications by authors named "L Bruschini"
Introduction: Asymmetric electromyographic (EMG) activity during teeth clenching has been linked to cognitive impairment, as evaluated by the Spinnler-Tognoni matrices test, and to asymmetric pupil size (anisocoria). Anisocoria indicates an asymmetric Locus Coeruleus activity, leading to an asymmetric hemispheric excitability worsening cognitive performance. Bite splint wearing corrects EMG asymmetry, reduces anisocoria and improves cognitive performance.
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- Congenital Cytomegalovirus (cCMV) is linked to serious long-term issues like hearing, vision, and neurodevelopmental problems, but there’s no standard approach for screening and treatment.
- This study reviewed data from newborns identified through targeted hearing screening, focusing on the long-term effects and any neurological abnormalities associated with cCMV over at least two years.
- Out of 61 newborns studied, 57.3% were symptomatic at birth, with a significant number developing sensorineural hearing loss, often accompanied by other complications, highlighting the need for effective monitoring and treatment strategies.
Overall survival, disease-free survival and quality of life in patients affected by HPV mediated p16+ oropharyngeal squamous cell carcinoma treated with upfront trans-oral robotic surgery vs radiotherapy or chemoradiotherapy.
Eur Arch Otorhinolaryngol
April 2024
Purpose: Treatment de-intensification for p16 + oropharyngeal squamous cell carcinoma (OPSCC) is an area of active research to reduce the side effects and improve patients' quality of life (QoL). In this paper we evaluated the Overall Survival (OS), the Disease-Free Survival (DFS) and the QoL of patients affected by p16 + OPSCC according to their prognostic stage group (PSG) and different treatments.
Methods: Patients were selected retrospectively through our Electronic Tumor Board Database according to prespecified inclusion criteria.
Implantable hearing devices in clinical practice. Systematic review and consensus statements.
Acta Otorhinolaryngol Ital
February 2024
Objective: Implantable hearing devices represent a modern and innovative solution for hearing restoration. Over the years, these high-tech devices have increasingly evolved but their use in clinical practice is not universally agreed in the scientific literature. Congresses, meetings, conferences, and consensus statements to achieve international agreement have been made.
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- Ossiculoplasty is a surgical procedure aimed at repairing the ossicular chain in the middle ear with prosthetics to improve hearing.
- This study investigates a new biohybrid prosthesis made of titanium and a bone extracellular matrix to enhance its performance and prevent extrusion, using human stem cells to test its effectiveness.
- Preliminary results show that the titanium scaffolds support the growth and differentiation of stem cells into bone-forming cells, suggesting potential for further research into this innovative approach for ear surgery.