Publications by authors named "L Bruch"

Article Synopsis
  • Sleep disordered breathing (SDB) is linked to worse heart recovery after a heart attack, prompting the TEAM-ASV I trial to assess the benefits of adding adaptive servo-ventilation (ASV) to standard care for patients with SDB post-acute myocardial infarction (AMI).
  • In the trial, 76 patients were divided into two groups: one received standard treatment, while the other added ASV starting a few days after their heart attack. Results showed that those using ASV had a significantly higher myocardial salvage index and reduced heart damage compared to the control group at 12 weeks.
  • Findings suggest that early ASV treatment can enhance heart recovery after an AMI for patients with SDB, but larger studies
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Objective: Patients surviving acute pulmonary embolism (PE) necessitate long-term treatment and follow-up. However, the chronic economic impact of PE on European healthcare systems remains to be determined.

Methods And Results: We calculated the direct cost of illness during the first year after discharge for the index PE, analyzing data from a multicentre prospective cohort study in Germany.

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Pulmonary hypertension associated with left heart disease (PH-LHD) corresponds to group two of pulmonary hypertension according to clinical classification. Haemodynamically, this group includes isolated post-capillary pulmonary hypertension (IpcPH) and combined post- and pre-capillary pulmonary hypertension (CpcPH). PH-LHD is defined by an mPAP > 20 mmHg and a PAWP > 15 mmHg, pulmonary vascular resistance (PVR) with a cut-off value of 2 Wood Units (WU) is used to differentiate between IpcPH and CpcPH.

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Article Synopsis
  • Extracorporeal Life Support (ECLS) is being used more for treating cardiogenic shock related to heart attacks, but its effect on survival rates is unclear.
  • In a multicenter trial, patients with an acute heart attack and planned revascularization were divided into two groups: one receiving ECLS along with standard treatment and the other receiving standard treatment alone, with death rates tracked after 30 days.
  • Results showed no significant difference in mortality between the two groups, but the ECLS group experienced higher rates of bleeding and vascular complications.
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