Rate of change in central corneal thickness: a viability indicator for conventional drainage tissues in organ culture.

Organ culture of human anterior segments is a powerful tool for understanding trabecular meshwork biology. However, data from a significant percentage of cultured anterior segments are unusable because tissues fail to meet quality control requirements, such as having adequate trabecular meshwork histology. The purpose of the present study was to evaluate a novel, real time method for assessing the viability of conventional drainage tissues in the human anterior segment perfusion model.

Reproducibility of self-measured intraocular pressure with the phosphene tonometer in patients with ocular hypertension and early to advanced glaucoma.

Purpose: To evaluate the reproducibility of self-measured intraocular pressure with the Proview tonometer in ocular hypertensives and early to advanced glaucoma patients.

Patients And Methods: Thirty-three patients with glaucoma and three with ocular hypertension (72 eyes) were prospectively enrolled. History of cornea surgery was the only exclusion criterion.

The glaucomas.

Glaucoma is the leading cause of irreversible blindness worldwide. The World Health Organization reported in 1995 that 5.1 million persons were bilaterally blind from glaucoma.

Effect of aging on optic nerve appearance: a longitudinal study.

Aim: To determine whether aging causes detectable changes in the appearance of the optic disc.

Methods: A retrospective longitudinal study was performed with quantitative and qualitative evaluations of digitised stereoscopic optic disc photographs of 224 eyes of 224 subjects. There were three groups: 100 normal subjects from the Framingham Eye Study, 68 glaucomatous patients followed longitudinally, and 56 normal subjects and glaucoma patients who had separate sets of disc photos taken on the same day.