Publications by authors named "L Brandi"
Different energy sources are often used in horse diets to enhance health and performance. Understanding how diet impacts the cecal and fecal microbiota is crucial for meeting the nutritional needs of horses. High-throughput sequencing and qPCR were used to compare the fecal and cecal microbiota of five healthy horses receiving three different diets: hay diet (HAY), hay + starch and sugar (SS), and hay + fiber and oil ingredients (FO).
View Article and Find Full Text PDFThe initiation phase is the rate-limiting step of protein synthesis (translation) and is finely regulated, making it an important drug target. In bacteria, initiation is guided by three initiation factors and involves positioning the start site on the messenger RNA within the P-site on the small ribosomal subunit (30S), where it is decoded by the initiator tRNA. This process can be efficiently inhibited by GE81112, a natural hydrophilic, noncyclic, nonribosomal tetrapeptide.
View Article and Find Full Text PDFBackground: This retrospective study aims to provide a comprehensive analysis of the demographics, survival rates, and therapeutic approaches of small-cell neuroendocrine carcinoma (SCNEC) and large-cell neuroendocrine carcinoma (LCNEC) while highlighting key differences compared to common urinary bladder cancers.
Methods: Our analysis utilized the Surveillance, Epidemiology, and End Results database (SEER), and data was collected from 2000-2020.
Results: A total of 1040 cases of urinary bladder SCNEC and LCNEC were identified.
Article Synopsis
- * Patients who had radical prostatectomy and preoperative MRI scans were analyzed, revealing a significant link between total prostate volume (TPV) and GVPZ, with 40 cc identified as the cutoff for small-to-moderate versus large prostates.
- * Findings suggest that larger BPH prostates may compress the peripheral zone, leading to glandular atrophy, and could potentially offer a protective effect against the growth of PCa, which commonly originates in the peripheral
In-depth understanding of intra- and postdialytic phosphate kinetics is important to adjust treatment regimens in hemodialysis. We aimed to modify and validate a three-compartment phosphate kinetic model to individual patient data and assess the temporal robustness. Intradialytic phosphate samples were collected from the plasma and dialysate of 12 patients during two treatments (HD1 and HD2).
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