Publications by authors named "L Borrego"
Article Synopsis
- Patch test outcomes can be affected by age, but there are mixed findings on how age impacts these results.
- The study involved over 13,000 patients and revealed that middle-aged adults (31-65 years) had the highest rates of positive skin sensitisation results, particularly for certain substances like nickel and potassium dichromate.
- Overall, while age does influence some patch test results, most allergens showed consistent reactivity across ages, underscoring the importance of standard testing regardless of age.
Endometriosis, a debilitating condition, affects one in ten women of reproductive age. Its pathophysiology remains unclear, though deficiencies in immune surveillance are thought to create an environment conducive to the evasion of ectopic endometrial cells from the immune system. Our research explores the immunological impact of endometriosis both locally and systemically, emphasizing natural killer (NK) and T cell subpopulations.
View Article and Find Full Text PDFBackground: Reports of allergic contact dermatitis (ACD) to phytonadione epoxide (PE) in cosmetics suggest that PE is as powerful a sensitiser as its parent compound phytonadione.
Objective: To evaluate a case series of ACD to PE in Spain.
Methods: We reviewed the records of 20 patients with ACD to cosmetics containing PE diagnosed across Spain between January 2019 and June 2023.
Article Synopsis
- Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are different inflammatory skin conditions, and the study aimed to explore their relationship further among patients referred for patch testing.
- Researchers analyzed data from the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC) to compare contact allergies and other clinical details between patients with AD and those without.
- The study found that while both groups showed similar allergy profiles, patients with AD had a lower likelihood of being sensitized to nickel sulphate compared to non-AD patients.
A re-assessment of the value of markers of corticosteroid contact allergy in the Spanish baseline series: Clobetasol propionate in the spotlight.
Contact Dermatitis
September 2024
Background: Budesonide and tixocortol pivalate as markers of contact allergy to corticosteroids have been questioned, as they are not able to detect a significant percentage of allergic patients.
Objectives: To investigate the potential role of clobetasol propionate in enhancing corticosteroid sensitisation detection.
Methods: Between January 2022 and December 2023, patients who attended centres involved in the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy were tested with an extended baseline series that included budesonide, tixocortol pivalate, clobetasol propionate 0.