Publications by authors named "L Book"
Article Synopsis
- - The study aimed to evaluate the effectiveness of short (<120 days) versus long (>180 days) antiviral prophylaxis for preventing cytomegalovirus (CMV) disease in pediatric liver transplant recipients by analyzing data from the Society of Pediatric Liver Transplantation registry between 2015 and 2019.
- - Among the 199 enrolled participants, shorter prophylaxis resulted in higher occurrences of CMV DNAemia (26.8% vs. 13.8%) and CMV syndrome (18.8% vs. 6.9%) compared to longer prophylaxis, while end-organ disease rates were similar between the two groups.
- - Long prophylaxis was associated with a significantly higher incidence of neutropenia (55
Effects of media portrayal on perceived cruise risk, image, and intentions.
Tour Manag Perspect
September 2023
This research examines how news media portrayal of Covid-19 cases on cruise ships can produce decision biases. Two experiments were conducted in which news stories were varied according to format, base rate, framing and number size. The results demonstrate that prior cruise experience increases travel intentions and cruise image and lowers perceptions of cruise risk.
View Article and Find Full Text PDFIntroduction: In July 2017, a policy to increase the use of segmental grafts (SGs) was implemented at our institution. The aim was to compare changes in waitlist activity after implementation of this policy.
Methods: A single-center, retrospective study.
Objectives: To determine whether neonatal conjugated or direct bilirubin levels were elevated in infants with biliary atresia (BA) and to estimate the number of newborns who would have positive screens in the nursery necessitating repeat testing after discharge.
Study Design: We used administrative data from a large integrated healthcare network in Utah to identify newborns who had a fractionated bilirubin recorded during birth admission from 2005 through 2019. Elevated conjugated bilirubin was defined as greater than 0.
Background And Aims: Detailed investigation of the biological pathways leading to hepatic fibrosis and identification of liver fibrosis biomarkers may facilitate early interventions for pediatric cholestasis.
Approach And Results: A targeted enzyme-linked immunosorbent assay-based panel of nine biomarkers (lysyl oxidase, tissue inhibitor matrix metalloproteinase (MMP) 1, connective tissue growth factor [CTGF], IL-8, endoglin, periostin, Mac-2-binding protein, MMP-3, and MMP-7) was examined in children with biliary atresia (BA; n = 187), alpha-1 antitrypsin deficiency (A1AT; n = 78), and Alagille syndrome (ALGS; n = 65) and correlated with liver stiffness (LSM) and biochemical measures of liver disease. Median age and LSM were 9 years and 9.