Publications by authors named "L Bohard"
Article Synopsis
- Alveolar echinococcosis (AE) is a rare, severe disease impacting over 18,000 people globally each year.
- Recent advancements in sequencing the mitochondrial genome of Echinococcus multilocularis have enabled researchers to explore the genetic diversity and evolution of the parasite.
- Analysis of 113 samples from various regions revealed four main haplogroups (HG1, HG2, HG3, and a potential HG4), with HG3 further divided into three micro-haplogroups, showing distinct geographical clusters and including new patient samples from areas outside historical endemic zones in France.
Alveolar echinococcosis (AE) is a parasitosis that is expanding worldwide, including in Europe. The development of genotypic markers is essential to follow its spatiotemporal evolution. Sequencing of the commonly used mitochondrial genes cob, cox1, and nad2 shows low discriminatory power, and analysis of the microsatellite marker EmsB does not allow nucleotide sequence analysis.
View Article and Find Full Text PDFTo describe the number of prosthetic joint infections (PJIs) with late documentation and to identify associated factors. Bacterial PJIs with surgical management between November 2015 and November 2019 in a French center were analyzed. Results of short (72 h) and late culture (at 14 days) were analyzed.
View Article and Find Full Text PDFAdaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients according to disease severity remain poorly characterized. To this end, we designed a prospective study (NCT04365322) that included 60 COVID-19 convalescent patients (1-month post infection) in two cohorts respectively entitled mild illness and severe pneumonia. The monitoring of peripheral immune responses was performed using IFNᵧ ELISpot assay.
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