Publications by authors named "L Blizzard"
Objectives: To describe the associations between OA-related biochemical markers and knee symptoms in middle-aged adults followed up over 10-13 years.
Methods: Blood samples were collected during the Childhood Determinants of Adult Health (CDAH)-1 study (year: 2004-06) and 10-13 year follow-up at CDAH-3. Serum samples from baseline (n=156) and follow-up (n=167) were analyzed for three OA-related biomarkers [cartilage oligomeric matrix protein (COMP), matrix metalloproteinase (MMP)-3, and hyaluronan (HA)] using non-isotopic enzyme-linked immunosorbent assay (ELISA).
Purpose: Many people living with multiple sclerosis (PwMS) experience poor sleep, which is associated with diminished overall health-related quality of life (HRQoL). We quantified associations between sleep quality and HRQoL domains and examined the extent to which other MS symptoms could account for these associations.
Methods: In this cross-sectional survey of 1,717 Australians with MS, we used Assessment of Quality of Life (AQoL) 8D and Pittsburgh Sleep Quality Index (PSQI) to assess HRQoL and sleep quality, respectively.
Article Synopsis
- The study investigates how increasing health spending in low-income countries leads to better health outcomes, but may experience diminishing returns at higher spending levels.
- Researchers used regression analysis to examine the relationship between health expenditures, health outcomes, and greenhouse gas emissions in healthcare across different countries.
- Findings suggest that while more investment in health can significantly improve health in poorer nations, excessive spending in wealthier countries may not produce similar benefits, highlighting a need to reconsider health spending strategies.
Article Synopsis
- - The study investigates the impact of sun exposure on the risk of progressive-onset multiple sclerosis (POMS) compared to relapse-onset multiple sclerosis (ROMS), finding that increased sun exposure is linked to a lower risk for both types.
- - Data was gathered from two nationwide studies, including environmental UV radiation exposure prior to the first MS symptoms among 153 POMS cases, 204 ROMS cases, and 558 control participants.
- - Results indicate that higher cumulative sun exposure reduces the onset risk for both POMS and ROMS, with a stronger effect observed for POMS, suggesting that lifelong sun exposure plays an important role in MS risk.
Background: Greater public transport use has been linked to higher physical activity levels. However, neither the amount of physical activity associated with each daily public transport trip performed, nor the potential total physical activity gain associated with an increase in trips/day, has been determined. Using objective measures, we aimed to quantify the association between public transport use, physical activity and sedentary time.
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