Despite the enormous achievements of Deep Learning (DL) based models, their non-transparent nature led to restricted applicability and distrusted predictions. Such predictions emerge from erroneous In-Distribution (ID) and Out-Of-Distribution (OOD) samples, which results in disastrous effects in the medical domain, specifically in Medical Image Segmentation (MIS). To mitigate such effects, several existing works accomplish OOD sample detection; however, the trustworthiness issues from ID samples still require thorough investigation.
View Article and Find Full Text PDFThe reprecipitation method, which is a solvent-exchange process, was used to prepare free-standing microcrystals from an organic fluorescent dye, 4-n-octylamino-7-nitrobenz-2-oxa-1,3-diazole. Calf thymus DNA was introduced as an additive into the reprecipitation medium, strongly accelerating the process. The reprecipitation kinetics was monitored by UV/vis absorption spectroscopy, and the analysis of the rate constants allowed the role played by the additive to be clarified.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
February 2004
The interaction between eosin and bovine serum albumin in buffer solution, at pH 7.4 has been studied by means of absorption and emission spectroscopy. Applying the Scatchard model to the absorbance data a non-linear plot was obtained, reflecting a complex process.
View Article and Find Full Text PDFThe interaction of haemin with reduced glutathione (GSH) was investigated in vitro and the association constant was determined by both spectrophotometric and interferometric methods. In order to elucidate the nature of this interaction, the reaction of haemin with a typical reductive agent (sodium dithionite) and a typical chelating agent for hem-iron (histidine) was also studied. Haemin-induced haemolysis in the presence and absence of GSH was monitored spectrophotometrically.
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