Publications by authors named "L Biertho"
Background: Magnetic digestive anastomosis has the potential to reduce anastomotic complications and complexity. We report the 1-year results of a new surgical technique using Self-forming Neodymium magnet Anastomosis Procedure with Sleeve gastrectomy (SNAP-S; GI Windows).
Methods: This was a prospective, nonrandomized multicenter trial.
Rise in plasma bile acids following hypoabsorptive bariatric surgeries predicts beneficial metabolic and homeostatic outcomes in male rats.
Am J Physiol Gastrointest Liver Physiol
December 2024
Article Synopsis
- The study evaluates how three types of bariatric surgeries—Roux-en-Y gastric bypass, biliopancreatic diversion with duodenal switch, and single anastomosis duodeno-ileal bypass—affect bile acid levels in male Wistar rats on different diets.
- Results show that these surgeries increase plasma levels of secondary bile acids, which are associated with reduced body weight and fat gain and improved glucose metabolism.
- Additionally, the findings highlight connections between bile acids and beneficial gut bacteria as well as short-chain fatty acids, suggesting these surgeries contribute to better metabolic health through these biochemical changes.
Obesity and its metabolic complications are associated with lower grey matter and white matter densities, whereas weight loss after bariatric surgery leads to an increase in both measures. These increases in grey and white matter density are significantly associated with post-operative weight loss and improvement of the metabolic/inflammatory profiles. While our recent studies demonstrated widespread increases in white matter density 4 and 12 months after bariatric surgery, it is not clear if these changes persist over time.
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- Recent guidelines on bariatric and metabolic surgery exist, but their quality is uncertain, prompting this study to assess them for perioperative care decisions.
- A thorough search of medical databases identified 26 guidelines for evaluation using the AGREE II framework, which measures guideline quality across several domains.
- Findings revealed mixed results: while guidelines were clear and targeted well, they often lacked stakeholder input, rigorous development, and attention to resource impacts, with only six guidelines scoring above 70%.*
Background: Among commonly performed bariatric surgeries, biliopancreatic diversion with duodenal switch (BPD-DS) provides greater weight loss than Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG), with sustained metabolic improvements. However, the risk of long-term nutritional deficiencies due to the hypoabsorptive component of BPD-DS hinders its widespread use.
Objective: The aim of the study was to examine nutritional status over 2 years after BPD-DS, RYGB or SG.