Paroxysmal nocturnal haemoglobinuria (PNH), although a rare type of acquired hemolytic anemia, can be life-threatening if not diagnosed early. Kidney involvement in PNH varies from reversible acute kidney injury to irreversible chronic damage. Here, we report a case of recurrent acute kidney injury in a young male requiring renal replacement support.
View Article and Find Full Text PDFIn India, poor health insurance coverage and high out-of-pocket expenditure especially for chronic and rare genetic/life-threatening diseases is a reality. People who use medical crowdfunding as an option to meet medical expenditures and the sudden growth of new fundraising platforms are significant developments in healthcare. The digital platforms in fundraising and the multitude of transactions they perform are increasing in the country and have a significant impact on the health sector and the rights of the patients which points toward the need for more effective regulation.
View Article and Find Full Text PDFBackground: Breast cancer is the second most commonly diagnosed cancer worldwide, with a high mortality rate in developing countries, including sub-Saharan Africa. Screening is one way to ensure early detection and management of breast cancer, and it is influenced by several factors. Education and socio-economic status may also affect the utilization of breast cancer screening services as these impact decision-making.
View Article and Find Full Text PDFBackground: Dopamine (D) and serotonin (5-HT) pathways contribute to psoriasis pathobiology. Disruptions incite increased inflammatory mediators, keratinocyte activation and deterioration, and worsening symptoms. Brilaroxazine (RP5063), which displays potent high binding affinity to D and 5-HT receptors and a moderate affinity to serotonin transporter (SERT), may affect the underlying psoriasis pathology.
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