Malignant fibrous histiocytoma with myofibroblastic differentiation of the vulva in an adolescent female.

Malignant fibrous histiocytoma is a rare sarcoma. Only seven cases in the vulva have been reported. We present a case of malignant fibrous histiocytoma of the vulva in an adolescent female.

Metastatic thyroid carcinoma masquerading as lacrimal gland tumor.

A 56-year-old woman presented with orbital signs and symptoms suggestive of lacrimal gland tumor. An excised biopsy specimen was obtained and showed glandular tissue, which could be confused with lacrimal gland acini. Closer microscopic examination and immunohistochemical studies revealed a metastatic tumor of thyroid gland origin.

Paget's disease of the nipple resembling an acantholytic disease on microscopic examination.

Two biopsies of an erosive lesion of the nipple had an appearance of an acantholytic disease without showing malignant cells. Only a third biopsy through the nipple with removal of a larger portion revealed some nests of atypical, large cells with clear cytoplasm, typical of Paget's disease. Immunohistochemical findings with carcinoembryonic antigen confirmed the diagnosis of Paget's disease of the nipple.

Thoracic sympathetic trunk compression by osteophytes associated with arthritis of the costovertebral joint. Anatomical and clinical considerations.

Hyperostosis (lipping) due to costovertebral arthritis was found frequently (84.3%) impinging on the sympathetic trunks (ganglia and cord), rami communicantes and roots of the splanchnic nerves on both sides of the spine in more than 1,000 dissecting room cadavers examined and 34 cadavers of adult and elderly people specially dissected. As a result of the compression, the affected sympathetic structures were angulated, deflected from their course, enlarged and often infiltrated with connective tissue.

Malignant cystic meningioma with spike and wave EEG pattern.

A 23 year old woman suffering from grand mal epilepsy showed generalized spike and wave activity on her EEG. The CT showed a cystic tumor in the cortex and the white tissue of the right parietal region. On operation the tumor was diagnosed as malignant infiltrating cystic meningioma.