Publications by authors named "L Bernal-Masferrer"

Background: Photodynamic therapy (PDT) is a widely-used non-surgical treatment for non-melanoma skin cancers, including basal cell carcinoma (BCC), actinic keratoses (AK), and Bowen's disease (BD). PDT has high success rates, but various factors, can influence treatment response. This study investigates the clinical, histological, and molecular factors that affect the efficacy of methyl aminolevulinate PDT (MAL-PDT) for BCC and BD.

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  • - Nail disorders in newborns can occur on their own or be a sign of broader health issues or genetic skin disorders, making their examination quite complex.
  • - The review discusses various nail changes that happen in newborns, including conditions like Beau's lines and onychoschizia, and stresses the importance of recognizing these changes for identifying serious underlying conditions.
  • - It also emphasizes the significance of certain hereditary diseases linked to nail abnormalities, such as nail-patella syndrome and congenital dyskeratosis, and explains how to differentiate between these conditions for accurate diagnosis.
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  • - This review explores various immunotherapeutic treatments for actinic keratoses (AKs), which are skin lesions caused by UV exposure, highlighting the immune-modulating effects of certain drugs like imiquimod and diclofenac.
  • - It discusses the effectiveness of treatments such as 5-fluorouracil and photodynamic therapy in healthy individuals, noting that their effectiveness is reduced in patients with weakened immune systems, like solid organ transplant recipients.
  • - The analysis emphasizes the potential of cryoimmunotherapy and introduces newer immunotherapies like resimiquimod and anti-PD1, but stresses that further research is needed to standardize their application.
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