In vivo osteoinductive effect and in vitro isolation and cultivation bone marrow mesenchymal stem cells.

Bone marrow contains cell type termed mesenchymal stem cells (MSC), first recognized in bone marrow by a German pathologist, Julius Cohnheim in 1867. That MSCs have potential to differentiate in vitro in to the various cells lines as osteoblast, chondroblast, myoblast and adipoblast cells lines. Aims of our study were to show in vivo capacity of bone marrow MSC to produce bone in surgically created non critical size mandible defects New Zeland Rabbits, and then in second part of study to isolate in vitro MSC from bone marrow, as potential cell transplantation model in bone regeneration.

Artificial creation of genetically identical individuals--reproductive cloning.

During the second half of the previous century, biologists were continuously searching for the answers to the questions about the creation of genetically identical individuals. From the very first ideas (Spemann, 1938) and the early reports on the attempts and successes in the reproductive cloning (Briggs and King, 1952; Stewart et al., 1958) to the recent news about the first cloned baby birth (published informally at the end of 2002), that topic gathered a significant scientific and non-scientific attention.

Impact of ABO blood groups on the fertility of different parental pairs.

Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions. Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples with different "a priori" and "a posteriori" risk assessment. The analysis points out that ABO blood groups can influence fertility of different parental pairs, and consequently--assessment of the individual pregnancy risk.

[ABO blood groups and haemolytic disease of newborns--population-genetic analysis].

Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions (e.g.--Matsunaga et al.

[Genetic counseling--a qualitative element in family planning].

The number of known hereditary diseases is constantly on the increase. In Yugoslavia, about 1800 children a year are estimated to be born with severe chromosomal anomalies (about 0.5% of all newborns).