ADA2 regulates inflammation and hematopoietic stem cell emergence via the AR pathway in zebrafish.

Deficiency of adenosine deaminase 2 (DADA2) is an inborn error of immunity caused by loss-of-function mutations in the adenosine deaminase 2 (ADA2) gene. Clinical manifestations of DADA2 include vasculopathy and immuno-hematological abnormalities, culminating in bone marrow failure. A major gap exists in our knowledge of the regulatory functions of ADA2 during inflammation and hematopoiesis, mainly due to the absence of an ADA2 orthologue in rodents.

[Consensus Document. Update on latex exposure and use of gloves in Italian health care settings].

This consensus document was prepared by an Italian working group including occupational health professionals involved for many years in the management of glove- and latex-related problems in health care settings. The aim of this document was to address the most significant technical, epidemiological, clinical, environmental and prevention problems related to the use of gloves and latex. The group's recommendations are based on scientific evidence and practical experience but they cannot be considered as final.

[Old and new types of sanitary gloves: what has improved?].

Background: During the eighties a large increase in latex gloves production was observed because of the high demand of gloves in health care settings. In this period a low compliance to minimal quality standard was detected and the poor glove quality was associated with an increase of both irritant and allergic glove-related diseases. Since the second half of nineties health care workers and manufacturers paid more attention to these problems and a trend to a gradual, even if slow, quality improvement was observed.

[Implementation of a health education programme in a sample of hairdressing trainees].

Background: Skin and respiratory diseases and upper limb cumulative trauma disorders are common in practising hairdressers but unfortunately also in hairdressing trainees. Recent data showed that prevention by education in this working area is of fundamental importance.

Objectives: The purpose of this study was to assess the knowledge that hairdressing trainees have of the risks present in their workplaces and to apply and verify, the efficacy of a specific educational programm

Methods: The programme was aimed at hairdressing trainees, aged from 15 to 21 years, attending 3 technical schools.

Prevention of latex allergy among health care workers and in the general population: latex protein content in devices commonly used in hospitals and general practice.

Background: In this study the latex protein content in devices commonly used in hospitals and general practice were investigated. The main aim was to acquire information for preventing latex allergy in health care workers and in the general population.

Methods: About 22 different types of medical devices and 23 devices commonly used in general practice were examined evaluating the total allergenic potency by a modified RAST-inhibition assay and quantitative determination of single allergens (Hev b1, Hev b5 and Hev b6.