Lactoferrin inhibits prostaglandin E2 secretion by breast milk macrophages.

The interaction between human breast milk macrophages and lactoferrin (LF) in its native form was studied in in vitro culture. Competitive inhibition-binding studies with 125I-LF and unlabeled LF showed that a specific receptor for LF was present on breast milk macrophages. LF at concentrations of 10(-6) -10(-9)M resulted in a dose-dependent inhibition of prostaglandin E2 secretion by breast milk macrophages (control-45 +/- 7; LF 10(-6)M -9 +/- 1 ng/ml/10(6) cells).

Bromsulfophthalein clearance and aminopyrine test in patients with Gilbert's syndrome.

Bromsulfophthalein (BSP) clearance and aminopyrine breath tests were performed in 13 patients with Gilbert's syndrome (GS) and six healthy volunteers. The BSP clearance was significantly lower in the GS patients (1.28 +/- 0.