Publications by authors named "L Barbin"
Article Synopsis
- Oceanic eddies are crucial in marine ecosystems, attracting diverse marine life, including predators, by concentrating forage fauna.
- In a study of a thousand eddies, only 13% showed significant effects on forage fauna, with just 6% exhibiting a strong "oasis effect."
- Both anticyclonic and cyclonic eddies can create oases, but only high-amplitude eddies with strong water-mass-trapping significantly impact marine life, indicating complex interactions that require more research.
Recent approaches in gait analysis involve the use of wearable motion sensors to extract spatio-temporal parameters that characterize multiple aspects of an individual's gait. In particular, the medical community could largely benefit from this type of devices as they could provide the clinicians with a valuable tool for assessing gait impairment. Motion sensor data are however complex and there is an urgent unmet need to develop sound statistical methods for analyzing such data and extracting clinically relevant information.
View Article and Find Full Text PDFBackground: Dementia with Lewy bodies remains underdiagnosed in clinical practice mainly because of the low sensitivity of existing diagnostic criteria and a strong overlap with Alzheimer's pathology that can mask the Lewy phenotype.
Objective: The objective of this study was therefore to develop and validate a new clinical scale designed to detect signs of Lewy body disease, called LeSCoD for Lewy body Screening scale in Cognitive Disorders.
Methods: 128 patients who fulfilled the clinical criteria of dementia with Lewy bodies (DLB; n = 32), Alzheimer's disease (AD; n = 77) or both (n = 19) was prospectively enrolled.
Controlling for confounding bias is crucial in causal inference. Distinct methods are currently employed to mitigate the effects of confounding bias. Each requires the introduction of a set of covariates, which remains difficult to choose, especially regarding the different methods.
View Article and Find Full Text PDFBackground: A recent controlled trial suggested that high-dose biotin supplementation reverses disability progression in patients with progressive multiple sclerosis.
Objective: To analyze the impact of high-dose biotin in routine clinical practice on disability progression at 12 months.
Methods: Progressive multiple sclerosis patients who started high-dose biotin at Nantes or Rennes Hospital between 3 June 2015 and 15 September 2017 were included in this prospective study.