Effects of chronic treatment with botulinum toxin type A in salivary glands of rats: Histological and immunohistochemical analyses.

Background: The intraglandular application of botulinum neurotoxin type A (BoNT-A) is used in patients with neuromotor disorders to control the escape of saliva. The aim of this study was to analyze the impact of repeated treatment with BoNT-A on the submandibular-sublingual complex of rats.

Methods: A total of 35 Wistar rats were divided into three groups: control group (C), in which animals were not treated; group B, treated with 2.

Evaluation of cytotoxicity and wound healing activity of Avicennia schaueriana in cream.

Avicennia schaueriana is found in Brazilian mangrove coast. The cytotoxicity in vitro of the Aqueous Extract of Leaves of Avicennia schaueriana (AELAs) and the healing activity of the plant in cream on mice skin wounds were evaluated in this study. The cytotoxic evaluation was performed on Vero cells.

Fluoxetine effects on periodontogenesis: histomorphometrical and immunohistochemical analyses in rats.

Objective: This study aimed to assess the effects of fluoxetine, a selective serotonin reuptake inhibitor, on the formation of the periodontal ligament during pregnancy and lactation in rat pups.

Material And Methods: Twelve pregnant rats of Wistar lineage were divided into four study groups. In the control group, 0.

Mast cell concentration and skin wound contraction in rats treated with Ximenia americana L.

Purpose: To evaluate wound contraction and the concentration of mast cells in skin wounds treated with wild plum (Ximenia americana) essential oil-based ointment in rats.

Methods: Sixty rats were submitted to two cutaneous wounds in the thoracic region, on the right and left antimeres. Thereon, they were divided into three groups: GX (wounds treated once a day with hydro alcoholic branch extract of Ximenia americana), GP (wounds that received vehicle), and GC (wounds without product application).

Histological and immunohistochemical findings of the action of botulinum toxin in salivary gland: systematic review.

The treatment of sialorrhea is necessary for the constant risks posed by hypersalivation. A new therapeutic option comes up with the application of botulinum toxin in salivary glands. However, little is known about its mechanism of action in glandular tissue.