This study explores the effect of preheating on the toughness of dissimilar welded joints between AISI 1037 and AISI 304 steels, using Shielded Metal Arc Welding (SMAW) and E309-16 electrodes. The innovation of this approach lies in assessing how preheating temperatures influence the mechanical properties of such welds. Preheating temperatures ranged from 150 °C to 300 °C, with impact testing revealing a notable increase in toughness, from 6.
View Article and Find Full Text PDFThe developmental origins of healthy and disease (DOHaD) concept has demonstrated a higher rate of chronic diseases in the adult population of individuals whose mothers experienced severe maternal protein restriction (MPR). Using proteomic and in silico analyses, we investigated the lung proteomic profile of young and aged rats exposed to MPR during pregnancy and lactation. Our results demonstrated that MPR lead to structural and immune system pathways changes, and this outcome is coupled with a rise in the PI3k-AKT-mTOR signaling pathway, with increased MMP-2 activity, and CD8 expression in the early life, with long-term effects with aging.
View Article and Find Full Text PDFMol Cell Endocrinol
July 2024
Maternal malnutrition can alter developmental biology, programming health and disease in offspring. The increase in sugar consumption during the peripubertal period, a worldwide concern, also affects health through adulthood. Studies have shown that maternal exposure to a low protein diet (LPD) is associated with an increase in prostate disease with aging.
View Article and Find Full Text PDFOral diseases are one of the biggest public health problems worldwide, caused by opportunistic pathogens such as and . (priprioca) is a plant conventionally used in traditional medicine in the Amazon region. However, little is known about the possible dentistry-related uses of extracts from the rhizomes and solid waste generated by the extraction of essential oils from this vegetable.
View Article and Find Full Text PDFThe developmental Origins of Health and Disease (DOHaD) concept has provided the framework to assess how early life experiences can shape health and disease throughout the life course. Using a model of maternal exposure to a low protein diet (LPD; 6% protein) during the gestational and lactational periods, we demonstrated changes in the ventral prostate (VP) transcriptomic landscape in young rats exposed to maternal malnutrition. Male offspring Sprague Dawley rats were submitted to maternal malnutrition during gestation and lactation, and they were weighed, and distance anogenital was measured, followed were euthanized by an overdose of anesthesia at 21 postnatal days.
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