Publications by authors named "L Baddour"

A distinction between infections of left ventricular assist devices (LVADs) and cardiac implantable electronic devices (CIEDs) is warranted as they differ markedly in incidence, microbiologic profiles, clinical presentations, and extraction feasibility. These differences necessitate tailored suppressive antibiotic therapy (SAT) strategies. This commentary highlights the need for device-specific SAT approaches.

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Cardiac implantable electronic device infection in the context of corynebacterial bloodstream infection (BSI) remains poorly understood. From 2012 to 2023 at Mayo Clinic, 4 of 12 patients with corynebacterial BSI had cardiac implantable electronic device infection: 1 patient was diagnosed during a relapsing BSI episode. Undefined source, persistent BSI, and the presence of a prosthetic cardiac valve were common characteristics.

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Article Synopsis
  • - Patients with bicuspid aortic valves (BAV) face a higher risk of infective endocarditis (IE), and this study investigates the differences in clinical features and microbiology between native valve endocarditis (NVE) in BAV patients and prosthetic valve endocarditis (PVE) in those who've had valve replacement.
  • - The study analyzed 161 patients with BAV and IE, finding that those with PVE tended to be older and had more underlying health issues compared to those with NVE, who had different microbial profiles and valve conditions.
  • - Key findings showed that Streptococcus mitis was the most common pathogen in NVE, while Staphylococcus aureus was prevalent in P
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