Unexplained bruising: a developing story.

We present the case of a 10-month-old male infant who presented to accident and emergency with unexplained bruising of the ear. Initial blood tests showed no clotting or platelet abnormalities and non-accidental injury investigation commenced. He was subsequently reviewed by the dermatology team who suggested the diagnosis of acute haemorrhagic oedema of infancy presumably triggered by a viral or bacterial infection, and the clinical findings fit this diagnosis.

An unusual case of seronegative, 16S PCR positive infection.

Introduction: is a zoonotic infection commonly diagnosed by isolation of the organism from blood culture or positive serological testing. It is an uncommon cause of a pyrexia of unknown origin in the United Kingdom.

Case Presentation: We describe the case of a 14-year-old girl with no history of travel who presented with pyrexia, weight loss, arthralgia, multiple splenic abscesses and a subsequent pleural effusion, the latter of which isolated a species on 16S rRNA PCR.

Magnetic resonance profiling of human skin in vivo using GARField magnets.

It is shown that one-dimensional magnetic resonance imaging (MRI-profiling) of human forearm and side-of-hand skin in vivo is possible using GARField magnets. Strong profile contrast originating from differing molecular mobility is seen for stratum corneum and viable epidermis. The first in vivo spatially-resolved field-gradient measurements of water self-diffusivity, D, in the stratum corneum (2.

GARField magnetic resonance profiling of the ingress of model skin-care product ingredients into human skin in vitro.

A preliminary study of the ingress of mineral oil, decanol, and glycerine into samples of human abdominal skin tissue in vitro made using magnetic resonance profiling with a GARField magnet is reported. Two layers, each circa 50 microm thick and attributed to stratum corneum and viable epidermis, are spatially resolved. Clear differences are observed in the magnetic resonance response of these layers arising from the application of the model skin-care product ingredients.