Structure-Optical Properties Relationships in Cobalt-Based Purple Pigments Used by Robert Delaunay.

Following the industrial revolution and the modernization of chemistry, purple became one of the most popular colors in the palettes of late 19th- to 20th-century painters. Among them, Robert Delaunay (1885-1941) was one of the key artists of the avant-garde movement in France in the early 20th century. Although widely used in modern and contemporary paintings, inorganic purple pigments of the cobalt phosphate and cobalt arsenate families have been little studied chemically until now.

AMPK protects proximal tubular epithelial cells from lysosomal dysfunction and dedifferentiation induced by lipotoxicity.

Renal proximal tubules are a primary site of injury in metabolic diseases. In obese patients and animal models, proximal tubular epithelial cells (PTECs) display dysregulated lipid metabolism, organelle dysfunctions, and oxidative stress that contribute to interstitial inflammation, fibrosis and ultimately end-stage renal failure. Our research group previously pointed out AMP-activated protein kinase (AMPK) decline as a driver of obesity-induced renal disease.

Stability of Diluted Desmopressin Acetate Intranasal Solution at 0.01 mg/mL.

Objective: In pediatrics, weight-based doses can be very small, leading to measuring tiny volumes of the commercial desmopressin nasal solution at 0.1mg/mL, which reduces precision and increases the risk of error. Since stability of the desmopressin acetate solution diluted at 0.

AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure.

Heart failure (HF) represents a multifaceted clinical syndrome characterized by the heart's inability to pump blood efficiently to meet the body's metabolic demands. Despite advances in medical management, HF remains a major cause of morbidity and mortality worldwide. In recent years, considerable attention has been directed toward understanding the molecular mechanisms underlying HF pathogenesis, with a particular focus on the role of AMP-activated protein kinase (AMPK) and protein O-GlcNAcylation.