Zh Vopr Neirokhir Im N N Burdenko
December 2024
Unlabelled: Glial cell line-derived neurotrophic factor (GDNF) is essential in maintaining the viability, function and differentiation of neuronal cells. In addition to its function in healthy nervous tissue, GDNF is involved in pathological processes, such as glioma growth. GDNF is represented by 2 main isoforms: pre-α-pro-GDNF (αGDNF) and pre-β-pro-GDNF (βGDNF).
View Article and Find Full Text PDFRecently, supramolecular self-assembly has attracted the attention of researchers worldwide because it enables the creation of nanostructures with unique properties without additional costs. Spontaneous organization of molecules allows the design and development of new nanostructures that can interact with drugs and living cells and generate a response. Therefore, supramolecular structures have enormous potential and can be in demand in various fields of healthcare and ecology.
View Article and Find Full Text PDFStimulus-responsive systems allowing for the controlled release of drugs [...
View Article and Find Full Text PDFLangmuir
October 2024
The low solubility of α-tocopherol in water and its susceptibility to photodegradation make it difficult for biological systems to absorb this natural antioxidant. To overcome these limitations, α-tocopherol was encapsulated in low-toxicity nanocontainers, namely, niosomes based on Tween 80 and cholesterol. The niosomes were modified with cationic surfactants containing a carbamate fragment.
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