Publications by authors named "L B Traylor"
Background: Sternal wound infections represent a source of significant morbidity and mortality following median sternotomy. The use of incisional negative pressure wound therapy in prevention has yet to be elucidated.
Methods: A retrospective study was conducted before and after a universal wound care protocol was implemented including the prophylactic use of negative pressure wound therapy (NPWT).
The COVID-19 pandemic has led to significant loss of life and severe disability, justifying the expedited testing and approval of messenger RNA (mRNA) vaccines. While found to be safe and effective, there have been increasing reports of myocarditis after COVID-19 mRNA vaccine administration. The acute events have been severe enough to require admission to the intensive care unit in some, but most patients fully recover with only rare deaths reported.
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- Immune checkpoint inhibition therapy has shown promise for improving outcomes in advanced non-small cell lung cancer, but there's a need for better predictive biomarkers; a blood test called host immune classifier (HIC) was evaluated for this purpose in a real-world study.* -
- The INSIGHT study enrolled over 3,570 NSCLC patients and assessed their survival based on HIC designation (HIC-H or HIC-C) and treatment type, revealing that HIC-H patients had significantly longer overall survival compared to HIC-C patients across various treatment regimens, including ICI therapies.* -
- The findings indicate that HIC testing can independently predict patient survival outcomes regardless of the programmed death ligand 1 (PD-L1)
Aims: A post-hoc analysis to assess the impact in people with type 2 diabetes, of increasing doses of basal insulin on glycaemic measures, body weight and hypoglycaemia.
Research Design And Methods: We included data from prospective, randomized controlled treat-to-target trials of ≥24 weeks' duration in people with type 2 diabetes, uncontrolled on metformin and sulphonylureas, and treated with insulin glargine 100 units/mL (U100), who had at least six fasting plasma glucose (FPG) measurements. The impact of insulin dose on glycated haemoglobin (HbA1c) values, FPG, hypoglycaemia incidence (<3.