[On the 100th anniversary of the death of Professor Ernô Emil Moravcsik (1858-1924) the founder of the Department of Neurology and Psychiatry at "Balassa" street].

Who was actually the director of the Department of Neurology and Psychiatry at Balassa Street, for a long time also referred to as the Moravcsik Clinic? A polymath, a genius, or rather a knight of fortune who wanted to draw attention to himself by building a clinic for himself? We looked into this on the occasion of his death anniversary. How did he get from the head of the department to the founding of the Psychiatry and Neurology Clinic? He dreamed up every corner of the Department, which was the most impressive and patient-friendly clinic of its time even in European terms. The building was not only used for the recovery of patients, but also for the continuous medical training of doctors.

Use and Costs of Supplemental Benefits in Medicare Advantage, 2017-2021.

Importance: Nearly all Medicare Advantage (MA) plans offer dental, vision, and hearing benefits not covered by traditional Medicare (TM). However, little is known about MA enrollees' use of those benefits or how much they cost MA insurers or enrollees.

Objective: To estimate use, out-of-pocket (OOP) spending, and insurer payments for dental, hearing, and vision services among Medicare beneficiaries.

Argonaute proteins regulate the timing of the spermatogenic transcriptional program.

Argonaute proteins are best known for their role in microRNA-mediated post-transcriptional gene silencing. Here, we show that AGO3 and AGO4, but not AGO2, localize to the sex chromatin of pachytene spermatocytes where they are required for transcriptional silencing of XY-linked genes, known as Meiotic Sex Chromosome Inactivation (MSCI). Using an mouse, we show that AGO3 and AGO4 are key regulators of spermatogenesis, orchestrating expression of meiosis-related genes during prophase I while maintaining silencing of spermiogenesis genes.

Application scenarios for a mobile hearing aid demonstrator with headphone form factor.

Objective: To describe application scenarios of a mobile device that provides a practical means for showcasing potential hearing aid benefits.

Design: A prototype of a hearing aid demonstrator based on circumaural headphones and a mobile signal processing platform was developed, providing core functions of a hearing aid, including several gain presets, in a hygienic, robust, and easy-to-use form factor. Speech intelligibility outcomes with the demonstrator and broadband level adaptations as potential fitting references were compared to outcomes with the own hearing aids of hearing-impaired participants.

Revolutionizing Diabetic Retinopathy Screening: Integrating AI-Based Retinal Imaging in Primary Care.

Diabetic retinopathy (DR) is a public health issue affecting millions in the United States and Europe. However, despite strong recommendations for screening at regular intervals by many professional societies, including the American Diabetes Association and the American Academy of Ophthalmology, screening rates remain suboptimal, with only 50-70% of patients with diabetes adhering to recommended annual eye exams. Barriers to screening include lack of awareness, socioeconomic factors, health care system fragmentation, and workforce shortages, among others.