Publications by authors named "L B PEARSON"

Objective: This review aims to formulate the most current, evidence-based recommendations regarding radiation therapy, radiosurgery, and chemotherapy for patients with metastatic spine tumors.

Methods: A systematic literature using PRISMA methodology was performed from 2010-2023 using the search terms "radiosurgery," "radiation therapy," "external beam radiation therapy," or "stereotactic body radiation therapy" in conjunction with "spinal," "spine," "metastasis," "metastases," or "metastatic."

Results: Spinal metastases should be managed in a multidisciplinary team consisting of spine surgeons, radiation oncologists, radiologists and oncologists.

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Severe bacterial infections (SBIs) are a leading cause of neonatal deaths in low- and middle-income countries. World Health Organization's (WHO's) guideline for outpatient management of danger signs indicating possible serious bacterial infections (PSBI) when referral is not possible was adopted by three pilot district councils in Mbeya Region, in Tanzania (Busekelo, Kyela and Mbarali Districts) in 2018 (the PSBI project). This study documented changes in practice during the PSBI project, and lessons learned.

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  • Fungal endophytes significantly enhance the health and productivity of both native and cultivated plants, but research on their communities in eucalypt species remains limited.
  • This study focused on the seasonal and spatial dynamics of fungal leaf endophytes in Eucalyptus crebra, finding that summer had significantly higher fungal diversity compared to autumn and spring.
  • The results revealed different fungal compositions across seasons and canopy levels, with Ascomycota being the most prevalent phylum year-round, and highlighted the importance of monitoring endophytic fungi for the health of E. crebra and similar species.
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  • Electronic patient-reported outcomes (ePROs) can enhance cancer patient care, but integrating them into clinical systems poses significant challenges, requiring technical resources, clinician and patient commitment, and institutional support.* -
  • The SIMPRO Research Consortium created and implemented eSyM, an ePRO-based symptom management program across six cancer centers, tracking implementation methods and barriers through established frameworks and tools like REDCap.* -
  • Out of 226 documented implementation strategies, 64 unique strategies were identified, with universal strategies that were consistently effective focusing on clinical preparation, training, and patient/clinician engagement being seen as particularly impactful.*
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