Publications by authors named "L B Lerma"

Article Synopsis
  • The discovery of extracellular vesicles (EVs) in mycobacterial species has revealed their critical roles in bacterial function and interactions with hosts, particularly in tuberculosis (TB).
  • Recent findings indicate that Mycobacterium tuberculosis (the TB-causing agent) produces EVs containing diverse biomolecules that can modulate immune responses and may have vaccine potential.
  • This minireview covers previous and new insights into the process of vesicle formation (vesiculogenesis), their content, and implications for understanding TB and developing diagnostic and therapeutic tools.
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Multiple tumors of different lineages merging into a single mass, termed collision tumors, are considered a rare phenomenon in the kidney. Tumor components, or partners, may be malignant (including metastatic disease), borderline, or benign. We report the largest cohort to date of 48 cases.

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Pathogenic and nonpathogenic mycobacteria secrete extracellular vesicles (EVs) under various conditions. EVs produced by ( ) have raised significant interest for their potential in cell communication, nutrient acquisition, and immune evasion. However, the relevance of vesicle secretion during tuberculosis infection remains unknown due to the limited understanding of mycobacterial vesicle biogenesis.

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(1) Background: Virtual reality and 3D printing are transforming orthopedic surgery by enabling personalized three-dimensional (3D) models for surgical planning and Patient-Specific Instruments (PSIs). Hospitals are establishing in-house 3D printing centers to reduce costs and improve patient care. Pediatric orthopedic surgery also benefits from these technologies, enhancing the precision and personalization of treatments.

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Bacterial membrane vesicles (BMVs) are important effectors in the pathogenesis, virulence, and biofilm formation during different bacterial infections. Because of their structure, BMVs can be applied as drug delivery systems (DDS) or in the production of immunogenic vaccines against different untreated diseases. In this sense, different antigens or immune stimulator molecules, such as proteins can be extracted for the development of such vaccines.

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