Placental concentrations of essential, toxic, and understudied metals and relationships with birth outcomes in Chattanooga, TN.

Background: Comprehensive examinations of placental metal concentrations and correlations with infant parameters are under-investigated. Chattanooga, Tennessee's consistently high incidence of low birth weight and potential for metal exposure provides an ideal opportunity to investigate potential correlations.

Objectives: To investigate the associations between a wide variety of metals in placental tissue and multiple infant parameters.

Identical twin marrow transplantation in multiple myeloma.

We performed the first successful syngeneic bone marrow transplantation (BM Txp) in a patient with multiple myeloma. The patient and his normal identical twin are 50-year-old physicians. Prior to BM Txp, a partial remission was achieved with 1 year of continuous low dosage melphalan and prednisone therapy.