Synthesis and Characterization of Antibacterial Poly{2-[(methacryloyloxy)ethyl]trimethylammonium Chloride}/Chitosan Semi-Interpenetrating Networks for Papain Release.

Annually, thousands of individuals suffer from skin injuries resulting from trauma, surgeries, or diabetes. Inadequate wound treatment can delay healing and increase the risk of severe infections. In this context, a promising synthetic polymer with potent antimicrobial properties, Poly{2-[(methacryloyloxy)ethyl]trimethylammonium chloride} (PMETAC), is synthesized and crosslinked with N,N'-Methylenebis(acrylamide) (BIS) in the presence of Chitosan (CH), a natural, biocompatible polysaccharide that promotes cell regeneration and provides additional beneficial properties.

Electrospun adsorbent membrane of PLA containing chitosan for toxic metal ions removal from aqueous solution: Effect of chitosan incorporation.

The scarcity of water resources and their pollution are vital to modern civilization. Thus, adsorptive membranes are promising candidates to be applied in the filtration systems to improve the water quality. In summary, this study investigated the effect of chitosan (CS) in the morphological, chemical, and physical aspects of PLA-based membranes incorporating chitosan obtained by electrospinning process, their adsorption behavior in multielement aqueous systems containing Cr, Cu, Zn, Mn , Ni, and Cd in pH 4, and the possible removal mechanism on the composite electrospun membrane's surface.

Association of 30-s Sit-to-Stand Power Test Outcome With Body Balance in Physically Active Older Adults.

Amount of serial sitting and standing movements has been employed in clinical and research settings to assess legs' muscular strength. In this cross-sectional study, we aimed to test the correlation between the 30-s sit-to-stand power test (30STSp) outcome and body balance in older adults. We evaluated physically active male and female (n = 51) individuals with an age range of 60-80 years (M = 69.

DPYD genotype should be extended to rare variants: report on two cases of phenotype / genotype discrepancy.

The enzyme dihydropyrimidine dehydrogenase (DPD) is the primary catabolic pathway of fluoropyrimidines including 5 fluorouracil (5FU) and capecitabine. Cases of lethal toxicity have been reported in cancer patients with complete DPD deficiency receiving standard dose of 5FU or capecitabine. DPD is encoded by the pharmacogene DPYD in which more than 200 variants have been identified.

Implementation of an Oncogeriatric Unit for Frail Older Patients with Breast Cancer: Preliminary Results.

(1) Background: Breast cancer (BC) has a high incidence in Europe, particularly in older adults. Traditionally under-represented in clinical trials, this age group is often undertreated due to ageism. This study aims to characterize frail older adults (≥70 years) with BC based on a comprehensive geriatric assessment, to guide individualized treatment decision-making.